Work is progressing on 125 West End Avenue, a conversion of an eight-story building into a 400,000-square-foot, state-of-the-art life sciences and research laboratory on Manhattan’s Upper West Side. Designed by Taconic Partners and Perkins+Will, the project involves interior renovations and the installation of a glass curtain wall. 125 West End Avenue was home to the Walt Disney/ABC broadcasting company since 1985, but had sat vacant since January. The structure was originally built as an automotive facility by Chrysler Motor Company and at one point was owned by the New York Times. Taconic and Nuveen Real Estate paid $230 million for the property in late 2019. CBRE is in charge of marketing and leasing the commercial office space, and JRM Construction Management, LLC is the general contractor for the project, which sits at the corner of West 66th Street and West End Avenue, a very short walk to Riverside Park South to the west.